Tag: Interaction Network

CIPHER – Correlating Protein Interaction Network and Phenotype Network to predict Disease Genes

CIPHER

:: DESCRIPTION

CIPHER, which stands for Correlating interactome and phenome networks to predict disease genes, is a computational framework we proposed to prioritize human disease genes. It was one of the first studies to explore interactome-phenome wide gene-disease relationships, and generated the first comprehensive genetic landscape of human disease,connecting 5080 human disease phenotypes with 14433 human genes.

::DEVELOPER

Wu Lab @ Columbia

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • MatLab

:: DOWNLOAD

NO

 :: MORE INFORMATION

Citation:

Mol Syst Biol. 2008;4:189. doi: 10.1038/msb.2008.27. Epub 2008 May 6.
Network-based global inference of human disease genes.
Wu X1, Jiang R, Zhang MQ, Li S.

GenePro 2.5.2 – Visualization and Analysis of Protein and Gene Interaction Networks

GenePro 2.5.2.

:: DESCRIPTION

GenePro is a Cytoscape plug-in for the visualization and analysis of protein and gene interaction networks at multiple levels of resolution.

::DEVELOPER

The Wodak Lab

:: SCREENSHOTS

:: REQUIREMENTS

:: DOWNLOAD

 GenePro

:: MORE INFORMATION

Citation

Vlasblom, J. et al.
GenePro: a cytoscape plug-in for advanced visualization and analysis of interaction networks.
Bioinformatics 22(17):2178-9 (2006).

BRAIN 1.0.5 /BRAIN Library 1.5 – Biologically Relevant Analysis of Interaction Networks

BRAIN 1.0.5 /BRAIN Library 1.5

:: DESCRIPTION

The BRAIN (Biologically Relevant Analysis of Interaction Networks) is a set of algorithms for predicting and analyzing protein domain-peptide ligand interactions based on experimentally known binding evidence (e.g. from protein chip or phage display experiments). BRAIN can be accessed as a Cytoscape plugin which reads peptide binding profiles and generates interactions displayed as a Cytoscape network.

::DEVELOPER

Bader Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 BRAIN /BRAIN Library

:: MORE INFORMATION

 

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