Filtering False Somatic Mutations from FFPE Tumor Sequencing data
:: DESCRIPTION
This program suite consists of 4 PERL programs made to identify and remove potential false positive somatic variants caused by FFPE (formalin-fixed paraffin-embedded) DNA damage on next-generation sequencing data.
::DEVELOPER
the Division of Genome Information Sciences, UCSD
:: SCREENSHOTS
N/A
:: REQUIREMENTS
- Linux/ WIndows/ MacOsX
- Perl
:: DOWNLOAD
:: MORE INFORMATION
Citation
Nucleic Acids Res. 2012 Aug;40(14):e107. Epub 2012 Apr 6.
Identification of high-confidence somatic mutations in whole genome sequence of formalin-fixed breast cancer specimens.
Yost SE, Smith EN, Schwab RB, Bao L, Jung H, Wang X, Voest E, Pierce JP, Messer K, Parker BA, Harismendy O, Frazer KA.
