fastsimcoal2 2.6.0.2 – Continuous-time Coalescent Simulator of Genomic Diversity

fastsimcoal2 2.6.0.2

:: DESCRIPTION

fastsimcoal is a new coalescent-based simulation program, which is able to quickly simulate a variety of genetic markers scattered over very long genomic regions with arbitrary recombination patterns under complex evolutionary scenarios.

::DEVELOPER

Computational and Molecular Population Genetics Lab, University of Bern

:: SCREENSHOTS

N/A

:: REQUIREMENTS

Windows / Linux / MacOsX
C++ Compiler

:: DOWNLOAD

fastsimcoal

:: MORE INFORMATION

Citation

Excoffier, L. and Foll, M (2011)
fastsimcoal: a continuous-time coalescent simulator of genomic diversity under arbitrarily complex evolutionary scenarios
Bioinformatics (2011)doi: 10.1093/bioinformatics/btr124

CT-CBN 0.1.04b – Continuous Time Conjunctive Bayesian Networks

CT-CBN 0.1.04b

:: DESCRIPTION

CT-CBN is a collection of two C programs, ct-cbn and h-cbn, that implement algorithms for model selection and maximum likelihood parameter estimation for continuous time conjunctive Bayesian networks. These graphical models have been designed to model the accumulation of mutations subject to constraints on the order in which the mutations can occur. The order constraints are encoded as a partially ordered set (poset) of genetic events. The waiting time for each event follows an independent exponential distribution.

::DEVELOPER

the Computational Biology Group (CBG)

:: SCREENSHOTS

N/A

:: REQUIREMENTS

Linux

:: DOWNLOAD

CT-CBN

:: MORE INFORMATION

Citation

Gerstung M, Baudis M, Moch H, Beerenwinkel N (2009).
Quantifying cancer progression with conjunctive Bayesian networks.
Bioinformatics 25(21):2809-2815.

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