L1pred – Prediction tool for Catalytic Residues in Enzymes

L1pred

:: DESCRIPTION

L1pred is a sequence-based prediction tool for catalytic residues in enzymes with the L1-logreg classifier

::DEVELOPER

System Biology Laboratory Of Chi Zhang

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 L1pred

 :: MORE INFORMATION

Citation

PLoS One. 2012;7(4):e35666. doi: 10.1371/journal.pone.0035666. Epub 2012 Apr 27.
L1pred: a sequence-based prediction tool for catalytic residues in enzymes with the L1-logreg classifier.
Dou Y1, Wang J, Yang J, Zhang C.

MEPI – Predict Catalytic Residues from Protein Structures

MEPI

:: DESCRIPTION

The MEPI is a web server to predict catalytic residues from protein structures, which integrates the Micro-Environment(ME) and Position Information of each residue.

::DEVELOPER

Ziding Zhang’s Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation:

PLoS One. 2012;7(7):e41370. doi: 10.1371/journal.pone.0041370. Epub 2012 Jul 19.
Identification of catalytic residues using a novel feature that integrates the microenvironment and geometrical location properties of residues.
Han L1, Zhang YJ, Song J, Liu MS, Zhang Z.

DISCERN – Catalytic Residue Prediction

DISCERN

:: DESCRIPTION

Discern is a method for catalytic residue prediction derived from the combination of three ingredients: the use of the INTREPID phylogenomic method to extract conservation information; the use of 3D structure data, including features computed for residues that are proximal in the structure; and a statistical regularization procedure to prevent overfitting.

::DEVELOPER

the Berkeley Phylogenomics Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Perl
  • Python

:: DOWNLOAD

  DISCERN

:: MORE INFORMATION

Citation

Sankararaman, S., Sha, F., Kirsch, J.F., Jordan, M.I., and Sjölander, K.,
Active Site Prediction using Evolutionary and Structural Information
Bioinformatics (2010) 26 (5): 617-624.; doi: 10.1093/bioinformatics/btq008

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