Pool-hmm 1.4.2 – Estimating Allele Frequencies and Detecting Selective Sweeps

Pool-hmm 1.4.2

:: DESCRIPTION

Pool-hmm aims at estimating allele frequencies and detecting selective sweeps, using NGS data from a sample of pooled individuals from the same population.

::DEVELOPER

Pool-hmm Team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows / MacOsX
  • Python

:: DOWNLOAD

 Pool-hmm

:: MORE INFORMATION

Citation

Mol Ecol Resour. 2013 Mar;13(2):337-40. doi: 10.1111/1755-0998.12063.
Pool-hmm: a Python program for estimating the allele frequency spectrum and detecting selective sweeps from next generation sequencing of pooled samples.
Boitard S, Kofler R, Fran?oise P, Robelin D, Schl?tterer C, Futschik A.

Drifter – Simulates Allele Frequencies using Forward-in-time Evolution under the Wright-Fisher model

Drifter

:: DESCRIPTION

Drifter simulates a forward-in-time Wright-Fisher model, and can be used to model genetic drift and explore the effects of sampling error given user-defined genetic frequency data.

::DEVELOPER

Professor Murray Cox, Massey University

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOsX /Windows
  • Perl

:: DOWNLOAD

 Drifter

:: MORE INFORMATION

Citation

Cox, M.P. 2006.
Extreme Patterns of Variance in Small Populations: Placing Limits on Human Y-Chromosome Diversity through Time in the Vanuatu Archipelago.
Annals of Human Genetics 71:390-406.

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