VTBuilder – Assembly of Multi Isoform Transcriptomes

VTBuilder

:: DESCRIPTION

VTBuilder is a tool for the inference of non-chimeric contigs from read data that has been sequenced from complex multi-isoformic transcriptomes, such as snake venom glands, or rapidly evolving viral populations, such as HIV-1.

::DEVELOPER

VTBuilder team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows / MacOsX
  • JRE

:: DOWNLOAD

 VTBuilder

:: MORE INFORMATION

Citation

BMC Bioinformatics. 2014 Dec 3;15(1):389.
VTBuilder: a tool for the assembly of multi isoform transcriptomes.
Archer JP, Whiteley G, Casewell NR, Harrison RA, Wagstaff SC.

NGS-Trex – NGS TRanscriptome profile EXplorer

NGS-Trex

:: DESCRIPTION

NGS-Trex is an automatic system for the analysis of NGS-Seq data.

::DEVELOPER

NGS-Trex team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

BMC Bioinformatics. 2013;14 Suppl 7:S10. doi: 10.1186/1471-2105-14-S7-S10. Epub 2013 Apr 22.
NGS-Trex: Next Generation Sequencing Transcriptome profile explorer.
Boria I1, Boatti L, Pesole G, Mignone F.

oposSOM 2.10.0 – Comprehensive Analysis of Transcriptome Data

oposSOM 2.10.0

:: DESCRIPTION

oposSOM translates microarray expression data into metadata of reduced dimension.

::DEVELOPER

Henry Wirth <wirth at izbi.uni-leipzig.de> and Martin Kalcher <mkalcher at porkbox.net>

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux /  MacOsX / Window
  • R
  • BioConductor

:: DOWNLOAD

 oposSOM

:: MORE INFORMATION

Citation

oposSOM: R-package for high-dimensional portraying of genome-wide expression landscapes on Bioconductor.
L?ffler-Wirth H, Kalcher M, Binder H.
Bioinformatics. 2015 Jun 10. pii: btv342

DISSECT 1.0.2 – Transcriptome-to-Genome Alignment Tool

DISSECT 1.0.2

:: DESCRIPTION

Dissect (DIScovery of Structural Alteration Event Containing Transcripts) is a transcriptome-to-genome alignment tool, which can identify and characterize transcriptomic events such as duplications, inversions, rearrangements and fusions. Dissect is suitable for whole transcriptome structural variation discovery problems involving sufficiently long reads or accurately assembled contigs.

::DEVELOPER

Lab for Bioinformatics and Computational Genomics

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

  DISSECT

:: MORE INFORMATION

Citation

Yorukoglu D, Hach F, Swanson L, Collins CC, Birol I, Sahinalp SC
Dissect: detection and characterization of novel structural alterations in transcribed sequences
Bioinformatics. 2012 Jun 15;28(12):i179-87

CEM 0.9.1 – Transcriptome Assembly and Isoform Expression Level Estimation from Biased RNA-Seq Reads

CEM 0.9.1

:: DESCRIPTION

CEM is an algorithm to assemble transcripts and estimate their expression levels from RNA-Seq reads.

::DEVELOPER

Wei Li

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Python

:: DOWNLOAD

 CEM

:: MORE INFORMATION

Citation

Bioinformatics. 2012 Nov 15;28(22):2914-21. doi: 10.1093/bioinformatics/bts559. Epub 2012 Oct 11.
Transcriptome assembly and isoform expression level estimation from biased RNA-Seq reads.
Li W1, Jiang T.

Annocript 1.1.3 – Annotation of Transcriptomes

Annocript 1.1.3

:: DESCRIPTION

Annocript is a pipeline for the annotation of de-novo generated transcriptomes. It executes BLAST analysis with UniProt, NCBI Conserved Domain Database and Nucleotide divisions, Gene Ontology, UniPathways and the Enzyme Commission

::DEVELOPER

frank Musacchia

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/ Windows
  • Perl

:: DOWNLOAD

 Annocript

:: MORE INFORMATION

Citation:

Annocript: a flexible pipeline for the annotation of transcriptomes also able to identify putative long noncoding RNAs.
Musacchia F, Basu S, Petrosino G, Salvemini M, Sanges R.
Bioinformatics. 2015 Feb 19. pii: btv106.

PsiCLASS 1.0.2 – Reference-based Transcriptome Assembler for Single or Multiple RNA-seq Samples

PsiCLASS 1.0.2

:: DESCRIPTION

PsiCLASS is a reference-based transcriptome assembler for single or multiple RNA-seq samples. Unlike conventional methods that analyze each sample separately and then merge the outcomes to create a unified set of meta-annotations, PsiCLASS takes a multi-sample approach, simultaneously analyzing all RNA-seq data sets in an experiment.

::DEVELOPER

Li Song

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • MacOsx/Linux

:: DOWNLOAD

PsiCLASS

:: MORE INFORMATION

Citation

Song L, Sabunciyan S, Yang G, Florea L.
A multi-sample approach increases the accuracy of transcript assembly.
Nat Commun. 2019 Nov 1;10(1):5000. doi: 10.1038/s41467-019-12990-0. PMID: 31676772; PMCID: PMC6825223.

Oqtans 0.1 beta – Online Quantitative Transcriptome Analysis

Oqtans 0.1 beta

:: DESCRIPTION

Oqtans is an integrative online platform for quantitatively analyzing RNA-Seq experiments. It is based on the Galaxy-framework and provides tools for read mapping, transcript reconstruction and quantitation as well as differential expression analysis

::DEVELOPER

the Biomedical Informatics Lab of Prof. Dr. Gunnar Rätsch

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/MacOsX

:: DOWNLOAD

 Oqtans

:: MORE INFORMATION

Citation:

Oqtans: the RNA-seq workbench in the cloud for complete and reproducible quantitative transcriptome analysis.
Sreedharan VT, Schultheiss SJ, Jean G, Kahles A, Bohnert R, Drewe P, Mudrakarta P, Görnitz N, Zeller G, Rätsch G.
Bioinformatics. 2014 May 1;30(9):1300-1. doi: 10.1093/bioinformatics/btt731.

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