Admixem v1.0.2.2 – Quality Assessment Tool for Metagenome Assemblies

Admixem v1.0.2.2

:: DESCRIPTION

Admix’em (Admixture simulator) is a new forward-time simulator that allows for rapid and realistic simulations of admixed populations with selection.

::DEVELOPER

Ray Cui

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux /  MacOsX
  • C++ COmpiler

:: DOWNLOAD

 Admixem

:: MORE INFORMATION

Citation

Admix’em: A flexible framework for forward-time simulations of hybrid populations with selection and mate choice.
Cui R, Schumer M, Rosenthal GG.
Bioinformatics. 2015 Nov 28. pii: btv700.

Ragout 2.3 – Tool for Reference-assisted Assembly

Ragout 2.3

:: DESCRIPTION

Ragout (Reference-Assisted Genome Ordering UTility) is a tool for assisted assembly using multiple references. It takes a short read assembly (a set of contigs), a set of related references and a corresponding phylogenetic tree and then assembles the contigs into scaffolds.

::DEVELOPER

Mikhail Kolmogorov

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux /  MacOsX / Windows
  • Python

:: DOWNLOAD

 Ragout

:: MORE INFORMATION

Citation

Ragout-a reference-assisted assembly tool for bacterial genomes.
Kolmogorov M, Raney B, Paten B, Pham S.
Bioinformatics. 2014 Jun 15;30(12):i302-i309. doi: 10.1093/bioinformatics/btu280.

ABRA 0.97 – Assembly Based ReAligner

ABRA 0.97

:: DESCRIPTION

ABRA is a realigner for next generation sequencing data. It uses localized assembly and global realignment to align reads more accurately, thus improving downstream analysis (detection of indels and complex variants in particular).

::DEVELOPER

ABRA team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/Windows/MacOsX
  • Java
  • C++ Compiler

:: DOWNLOAD

 ABRA

:: MORE INFORMATION

Citation:

ABRA: improved coding indel detection via assembly based re-alignment.
Mose LE, Wilkerson MD, Hayes DN, Perou CM, Parker JS.
Bioinformatics. 2014 Jun 6. pii: btu376

NOmESS – Homology-driven Assembly of NOn-redundant protEin Sequence Sets

NOmESS

:: DESCRIPTION

NOmESS is a homolgy-driven assembly tool to create a NOn-redundant protEin Sequence Set for mass spectrometry.

::DEVELOPER

Jürgen Cox

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows 64bit
  • .NET Framework 4.5

:: DOWNLOAD

 NOmESS

:: MORE INFORMATION

Citation

Homology-driven assembly of NOn-redundant protEin Sequence Sets (NOmESS) for mass spectrometry.
Temu T, Mann M, Räschle M, Cox J.
Bioinformatics. 2016 Jan 6. pii: btv756.

CodonCode Aligner 9.0.2 – DNA Sequence Assembly & Alignment

CodonCode Aligner 9.0.2

:: DESCRIPTION

CodonCode Aligner is a program for sequence assembly, contig editing, and mutation detection, available for Windows and Mac OS X. Aligner is compatible with Phred-Phrap and fully supports sequence quality scores, while offering a familiar, easy-to-learn user interface.

::DEVELOPER

CodonCode Corporation

:: SCREENSHOTS

:: REQUIREMENTS

  • Windows/Mac OsX

:: DOWNLOAD

CodonCode Aligner

:: MORE INFORMATION

Metassembler 1.5 – Combines multiple Whole Genome de novo Assemblies into a combined Consensus Assembly

Metassembler 1.5

:: DESCRIPTION

Metassembler is a software package for reconciling assemblies produced by de novo short-read assemblers such as SOAPdenovo and ALLPATHS-LG. The goal of assembly reconciliation, or “metassembly,” is to combine multiple assemblies into a single genome that is superior to all of its constituents

::DEVELOPER

Schatz Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 Metassembler

:: MORE INFORMATION

Citation

Genome Biol. 2015 Sep 24;16:207. doi: 10.1186/s13059-015-0764-4.
Metassembler: merging and optimizing de novo genome assemblies.
Wences AH, Schatz MC

pilon v1.24 – Automated Assembly Improvement

pilon v1.24

:: DESCRIPTION

pilon uses read alignment analysis to diagnose, report, and automatically improve de novo genome assemblies.

::DEVELOPER

The Broad Institute

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / MacOsX / Linux
  • Java

:: DOWNLOAD

 pilon

:: MORE INFORMATION

Citation

Pilon: an integrated tool for comprehensive microbial variant detection and genome assembly improvement.
Walker BJ, Abeel T, Shea T, Priest M, Abouelliel A, Sakthikumar S, Cuomo CA, Zeng Q, Wortman J, Young SK, Earl AM.
PLoS One. 2014 Nov 19;9(11):e112963. doi: 10.1371/journal.pone.0112963.

Phusion 2.1c – Assembly Genome Sequences from Whole Genome Shotgun(WGS) Reads

Phusion 2.1c

:: DESCRIPTION

Phusion is a software package for assembling genome sequences from whole genome shotgun(WGS) reads.

::DEVELOPER

Phusion team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 Phusion

:: MORE INFORMATION

Citation

The phusion assembler.
Mullikin JC and Ning Z
Genome research2003;13;1;81-90

MindTheGap 2.2.3 – Detection and Assembly of Insertion Variants

MindTheGap 2.2.3

:: DESCRIPTION

MindTheGap is a software that performs detection and assembly of DNA insertion variants in NGS read datasets with respect to a reference genome.

::DEVELOPER

MindTheGap team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOsX

:: DOWNLOAD

 MindTheGap

:: MORE INFORMATION

Citation:

MindTheGap : integrated detection and assembly of short and long insertions.
Rizk G, Gouin A, Chikhi R, Lemaitre C.
Bioinformatics. 2014 Aug 14. pii: btu545

IsoSCM 2.0.12 – Transcript Assembly tool using Multiple Change-point Inference to improve 3’UTR Annotation

IsoSCM 2.0.12

:: DESCRIPTION

IsoSCM (Isoform Structural Change Model) is a new method for transcript assembly  that incorporates change-point analysis to improve the 3′ UTR annotation process.

::DEVELOPER

IsoSCM team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux /Windows
  • Java

:: DOWNLOAD

  IsoSCM

:: MORE INFORMATION

Citation

RNA. 2015 Jan;21(1):14-27. doi: 10.1261/rna.046037.114. Epub 2014 Nov 18.
IsoSCM: improved and alternative 3′ UTR annotation using multiple change-point inference.
Shenker S, Miura P, Sanfilippo P, Lai EC

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