Phyre 2.0
:: DESCRIPTION
Phyre2 is a major update to the original Phyre server. As with Phyre, the new system is designed around the idea that you have a protein sequence/gene and want to predict its three-dimensional (3D) structure. Whereas Phyre used a profile-profile alignment algorithm, Phyre2 uses the alignment of hidden Markov models via HHsearch1 to significantly improve accuracy of alignment and detection rate.
::DEVELOPER
Structural Bioinformatics Group, Imperial College
:: SCREENSHOTS
N/A
:: REQUIREMENTS
- Web Browser
:: DOWNLOAD
:: MORE INFORMATION
Citation:
The Phyre2 web portal for protein modeling, prediction and analysis.
Kelley LA, Mezulis S, Yates CM, Wass MN, Sternberg MJ.
Nat Protoc. 2015 Jun;10(6):845-58. doi: 10.1038/nprot.2015.053.
Protein structure prediction on the Web: a case study using the Phyre server.
Kelley LA, Sternberg MJ.
Nat Protoc. 2009;4(3):363-71. doi: 10.1038/nprot.2009.2.