PhyloGibbs 1.2
:: DESCRIPTION
PhyloGibbs is an algorithm for discovering regulatory sites in a collection of DNA sequences, including multiple alignments of orthologous sequences from related organisms. Many existing approaches to either search for sequence-motifs that are overrepresented in the input data, or for sequence-segments that are more conserved evolutionary than expected. PhyloGibbs combines these two approaches and identifies significant sequence-motifs by taking both over-representation and conservation signals into account.
PhyloGibbs-MP is a significant enhancement.
::DEVELOPER
:: SCREENSHOTS
N/A
:: REQUIREMENTS
- Linux / Windows/ MacOsX
:: DOWNLOAD
:: MORE INFORMATION
Citation:
Rahul Siddharthan, Eric D. Siggia, and Erik van Nimwegen
PhyloGibbs: A Gibbs Sampling Motif Finder That Incorporates Phylogeny
PLoS Comput Biol 1(7): e67 2005