XAEM 0.1.1

:: DESCRIPTION

XAEM implements the design matrix and alternating EM (AEM) algorithm, which allows a fast and accurate quantification of isoform expression using multiple samples. In differential expression (DE) analysis of single-cell data XAEM substantially outperforms other methods.

::DEVELOPER

PROF. YUDI PAWITAN

:: SCREENSHOTS

N/A

:: REQUIREMENTS

• Linux
• R

:: DOWNLOAD

XAEM

:: MORE INFORMATION

Citation

Deng W, Mou T, Kalari KR, Niu N, Wang L, Pawitan Y, Vu TN.
Alternating EM algorithm for a bilinear model in isoform quantification from RNA-seq data.
Bioinformatics. 2020 Feb 1;36(3):805-812. doi: 10.1093/bioinformatics/btz640. PMID: 31400221.