TWAIN – Syntenic Gene Finder

TWAIN

:: DESCRIPTION

TWAIN is a software to predict genes simultaneously in two closely related eukaryotic organisms.TWAIN is a new syntenic genefinder which employs a Generalized Pair Hidden Markov Model (GPHMM) to predict genes in two closely related eukaryotic genomes simultaneously.It utilizes the MUMmer package to perform approximate alignment before applying a GPHMM based on an enhanced version of the TigrScan gene finder.

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::DEVELOPER

Bill Majoros and Mihaela Pertea while at the J. Craig Venter Institute

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

TWAIN

:: MORE INFORMATION

Citation

Majoros W.H., Pertea M., Salzberg S.L. (2005) Efficient implementation of a Generalized Pair Hidden Markov Model for comparative gene findingBioinformatics 21 1782-1788.

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