TWAIN
:: DESCRIPTION
TWAIN is a software to predict genes simultaneously in two closely related eukaryotic organisms.TWAIN is a new syntenic genefinder which employs a Generalized Pair Hidden Markov Model (GPHMM) to predict genes in two closely related eukaryotic genomes simultaneously.It utilizes the MUMmer package to perform approximate alignment before applying a GPHMM based on an enhanced version of the TigrScan gene finder.
::DEVELOPER
Bill Majoros and Mihaela Pertea while at the J. Craig Venter Institute
:: SCREENSHOTS
N/A
:: REQUIREMENTS
:: DOWNLOAD
:: MORE INFORMATION
Citation
Majoros W.H., Pertea M., Salzberg S.L. (2005) Efficient implementation of a Generalized Pair Hidden Markov Model for comparative gene finding. Bioinformatics 21 1782-1788.