UNPHASED 3.1.7 – Association Analysis in Nuclear Families and Unrelated Subjects

UNPHASED 3.1.7

:: DESCRIPTION

UNPHASED is an application for performing genetic association analysis in nuclear families and unrelated subjects. It implements maximum-likelihood inference on haplotype and genotype effects while allowing for uncertain phase and missing genotypes. Many of the commonly performed analyses are provided including transmission/disequilbrium tests, global and individual tests for haplotypes, tests that account for associations of nearby loci, tests of gene-gene interaction, adjustments for environmental covariates, genotype tests, comparison of risk between different haplotypes, and permutation tests.

::DEVELOPER

Frank Dudbridge

:: SCREENSHOTS

:: REQUIREMENTS

  • Linux/windows/MacOsX
  • Java

:: DOWNLOAD

 UNPHASED

:: MORE INFORMATION

Citation

Dudbridge F (2008)
Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data.
Hum Hered 66:87-98

MAGprediction – Gene Allele Prediction Using Unphased SNP data

MAGprediction

:: DESCRIPTION

MAGprediction (Multi-allelic Gene Prediction) is a software which was developed for predicting highly polymorphic gene alleles using unphased SNP data.

::DEVELOPER

Fred Hutchinson Cancer Research Center

:: SCREENSHOTS

:: REQUIREMENTS

:: DOWNLOAD

 MAGprediction

:: MORE INFORMATION

Citation

Li SS, Wang H, Smith A, Zhang B, Zhang XC, Schoch G, Geraghty D, Hansen JA, Zhao LP
Predicting Highly Polymorphic Alleles Using Unphased and Flanking Single Nucleotide Polymorphisms.
Genetic Epidemiology 2011,35(2):85-92