TSpred – Predict Substitutions that Transform Query Protein Sequence/structure into Temperature-sensitive Mutant

TSpred

:: DESCRIPTION

TSpred attempts to identify a small set of amino acid residues in a query protein that have a high probability of being buried (side-chain accessibilities less than 5%, expressed in terms of residue depth). The server suggests substitutions at these buried positions that are most likely to result in a temperature sensitive (Ts) phenotype.

::DEVELOPER

Bioinformatics Institute of Singapore.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation:

Nucleic Acids Res. 2014 Apr 29. [Epub ahead of print]
TSpred: a web server for the rational design of temperature-sensitive mutants.
Tan KP1, Khare S, Varadarajan R, Madhusudhan MS.