MALDSoft 1.0 – Admixture Mapping of Complex Trait Loci

MALDSoft 1.0

:: DESCRIPTION

MALDSoft is a program for admixture mapping of complex trait loci, using case-control data. The samples should come from a recently-admixed; population; additional ‘learning’ samples from the parental populations are helpful.

::DEVELOPER

Pritchard Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

  MALDSoft

:: MORE INFORMATION

Citation:

Giovanni Montana and Jonathan K. Pritchard, 2004.
Statistical Tests for Admixture Mapping with Case-Control and Cases-Only Data
Am J. Hum Genet. 75:771 -789

TreeLD 1.0.1 – Map Complex Trait Loci

TreeLD 1.0.1

:: DESCRIPTION

TreeLD is a free software tool for mapping complex trait loci. TreeLD performs a multipoint LD-analysis by inferring the ancestry of a genomic region and analyzing this ancestry for signals of disease mutations. The generated likelihoods can be used to test for the presence of a disease locus and to fine-map its location, providing a point estimate and a credible region. Furthermore, the package provides a novel way of visualizing the association signal in a sample. TreeLD is designed for high-density SNP haplotypes and can be applied to case-control data, TDT trio data and quantitative trait data.

::DEVELOPER

Pritchard Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux /  Windows

:: DOWNLOAD

  TreeLD

:: MORE INFORMATION

Citation

Sebastian Zöllner, Xiaoquan Wen, and Jonathan K. Pritchard
Association mapping and fine mapping with TreeLD
Bioinformatics. 2005 July 15; 21(14): 3168–3170.

HTreeQA 1.0 – using semi-perfect Phylogeny Trees in Quantitative Trait loci study on Genotype data

HTreeQA 1.0

:: DESCRIPTION

HTreeQA uses semi-perfect phylogeny trees in quantitative trait loci study on genotype data

::DEVELOPER

Wei Wang

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 HTreeQA

:: MORE INFORMATION

Citation

G3 (Bethesda). 2012 Feb;2(2):175-89. doi: 10.1534/g3.111.001768. Epub 2012 Feb 1.
HTreeQA: Using Semi-Perfect Phylogeny Trees in Quantitative Trait Loci Study on Genotype Data.
Zhang Z, Zhang X, Wang W.