StatSigMA beta / StatSigMA-w v2
:: DESCRIPTION
StatSigMA (Statistical Significance of Multiple Alignments) computes the statistical significance of multiple sequence alignments (of either nucleotide or amino acid sequences), much as BLAST’s E-values provide statistical significance for pairwise alignments.
StatSigMA-w (Statistical Significance of Whole-Genome Multiple Alignments),Given any multiple sequence alignment and a phylogeny of the aligned sequences, assesses the accuracy of the alignment and identifies suspiciously aligned regions.
::DEVELOPER
The Computational & Synthetic Biology group – COMPUTER SCIENCE & ENGINEERING at UNIVERSITY OF WASHINGTON
:: SCREENSHOTS
Command Line
:: REQUIREMENTS
- Linux
- GCC
:: DOWNLOAD
:: MORE INFORMATION
Citation:
A. Prakash, M. Tompa,
“Assessing the discordance of multiple sequence alignments“,
IEEE/ACM Trans Comput Biol Bioinform, vol. 6 (2009) 542-51.Pubmed 19875854.
X. Chen, M. Tompa,
“Comparative assessment of methods for aligning multiple genome sequences“,
Nat. Biotechnol., vol. 28 (2010) 567-72.