SSC 0.1 – Sequence Scan for CRISPR

SSC 0.1

:: DESCRIPTION

SSC is a tool for predicting sgRNA efficiency from spacer sequences. It supports the applications of optimizing sgRNA libraries in CRISPR/Cas9 knockout or CRISPR/dCas9 inhibition/activation screens.

::DEVELOPER

X. Shirley Liu Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 SSC

:: MORE INFORMATION

Citation

Genome Res. 2015 Aug;25(8):1147-57. doi: 10.1101/gr.191452.115. Epub 2015 Jun 10.
Sequence determinants of improved CRISPR sgRNA design.
Xu H, Xiao T, Chen CH, Li W, Meyer CA, Wu Q, Wu D, Cong L, Zhang F, Liu JS, Brown M, Liu XS.

SSC 0.6 – Stochastic Simulation Compiler

SSC 0.6

:: DESCRIPTION

SSC (Stochastic Simulation Compiler) is a tool for creating exact stochastic simulations of biochemical reaction networks. The models are written in a succinct, intuitive format, where reactions are specified with patterns. Patterns mention only the part of the compound relevant to a given reaction, and correspond to an intuitive view of biochemical reactions. This enables complex biochemical signaling networks to be specified without the knowledge of any formal programming languages.

::DEVELOPER

Lis, Mieszko; Artyomov, Maxim N.; Chakraborty, Arup K.; Devadas, Srinivas @ MIT

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

SSC

:: MORE INFORMATION

Citation:

Lis, Mieszko et al. “Efficient stochastic simulation of reaction–diffusion processes via direct compilation.” Bioinformatics 25.17 (2009): 2289 -2291.