SRMA 1.0.0-2 – Analyze Array-based Sequencing data for Identifying Rare DNA Variants

SRMA 1.0.0-2

:: DESCRIPTION

SRMA is an R package for resequencing microarray data analysis that integrates a novel statistical algorithm, sequence robust multi-array analysis, for rare variant detection with high sensitivity and accuracy.

::DEVELOPER

Statistical Bioinformatics Lab, The University of Texas M. D. Anderson Cancer Center

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux /MacOsX
  • R package

:: DOWNLOAD

  SRMA

:: MORE INFORMATION

Citation

SRMA: an R package for resequencing array data analysis.
Zhang N, Xu Y, O’Hely M, Speed TP, Scharfe C, Wang W.
Bioinformatics. 2012 Jul 15;28(14):1928-30. doi: 10.1093/bioinformatics/bts286

SRMA 0.1.15 – Sequence Re-alignment for Next Generation Sequencing

SRMA 0.1.15

:: DESCRIPTION

SRMA (Short Read Micro re-Aligner) is a software package that performs sequence re-alignment for next generation sequencing technology.It fixes artifacts introduced by aligning each read independently, significantly reducing the false positive detection, while cleaning insertions and deletions.

::DEVELOPER

Nils Homer

:: SCREENSHOTS

:: REQUIREMENTS

  • Windows / Linux / Mac OsX
  • Java

:: DOWNLOAD

SRMA

:: MORE INFORMATION

Citation:

Homer N, Nelson SF.
Improved variant discovery through local re-alignment of short-read next-generation sequencing data using SRMA.
Genome Biol. 2010 Oct 8;11(10):R99 PMID: 20932289