SLINK 3.02 – Simulation program for Linkage Analysis

SLINK 3.02

:: DESCRIPTION

The program SLINK is a general computer simulation program that employs a variation of the algorithm described by Ott (1989).  Suppose there are N people in a pedigree.  Let x = (x1,x2,…,xN) represent the vector of phenotypes of the N people in the pedigree.  Likewise, let g = (g1, g2,…,gN) represent the vector of multi-locus genotypes including phase information.

::DEVELOPER

Division of Statistical Genetics

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / Linux / MacOS
  • C++ Compiler
  • LINKAGE

:: DOWNLOAD

  SLINK

:: MORE INFORMATION

Citation:

Hum Hered. 2011;71(2):126-34. doi: 10.1159/000324177. Epub 2011 Jul 6.
Coordinated conditional simulation with SLINK and SUP of many markers linked or associated to a trait in large pedigrees.
Schäffer AA1, Lemire M, Ott J, Lathrop GM, Weeks DE.

Weeks DE, Ott J, Lathrop GM (1990)
SLINK: a general simulation program for linkage analysis.
Am J Hum Genet 47:A204

SUP 20110711 – SLINK/FastLINK Utility Program

SUP 20110711

:: DESCRIPTION

SUP is an extension to SLINK to allow a larger number of marker loci to be simulated in pedigrees conditional on trait values and in linkage equilibrium or disequilibrium with a trait locus.

::DEVELOPER

Mathieu Lemire

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • C Compiler

:: DOWNLOAD

 SUP

:: MORE INFORMATION

Citation

SUP: an extension to SLINK to allow a larger number of marker loci to be simulated in pedigrees conditional on trait values.
Lemire M.
BMC Genet. 2006 Jul 3;7:40.