VERA & SAM 1.0 – Find Significant Expression Differences in DNA Microarray Data

VERA & SAM 1.0

:: DESCRIPTION

VERA & SAM (Variability and ERror Assessment and Significance of Array Measurement) Estimates error model parameters from replicated, preprocessed experiments, and  uses error model to improve the accuracy of the expression ratio and to assign a value ‘lambda’ to each gene, indicating the likelihood that the gene is differentially expressed.

VERA and SAM are a pair of programs that provide a method to determine whether any given gene is expressed at a different level in one cell population than in another according to microarray data.

::DEVELOPER

the Ideker Lab

:: SCREENSHOTS

:: REQUIREMENTS

  • Linux / Windows

:: DOWNLOAD

VERA & SAM

:: MORE INFORMATION

Citation

T. Ideker, V. Thorsson, A. F. Siegel, and L. Hood.
Testing for differentially-expressed genes by maximum-likelihood analysis of microarray data
Journal of Computational Biology 7 (6) 805-817 (2000).