TreqCG 0.3 – Clustering Accelerates High-Throughput Sequencing Read Mapping

TreqCG 0.3

:: DESCRIPTION

TreqCG is a method to accelerate and improve read mapping based on an initial clustering of up to billions of high-throughput sequencing reads yielding clusters of high stringency and a high degree of overlap.

::DEVELOPER

Schliep lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • GCC

:: DOWNLOAD

 TreqCG

:: MORE INFORMATION

Citation

Mahmud, Md and Schliep, Alexander.
TreQ-CG: Clustering Accelerates High-Throughput Sequencing Read Mapping (2014)

HMM-FRAME 20140724 – Protein Domain Classification for Sequencing Reads with Frameshift Errors

HMM-FRAME 20140724

:: DESCRIPTION

HMM-FRAME is a protein domain classification tool based on an augmented Viterbi algorithm that can incorporate error models from different sequencing platforms. HMM-FRAME corrects sequencing errors and classifies putative gene fragments into domain families. It achieved high error detection sensitivity and specificity in a data set with annotated errors.

::DEVELOPER

Yanni Sun

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • G++

:: DOWNLOAD

 HMM-FRAME

:: MORE INFORMATION

Citation

BMC Bioinformatics. 2011 May 24;12:198. doi: 10.1186/1471-2105-12-198.
HMM-FRAME: accurate protein domain classification for metagenomic sequences containing frameshift errors.
Zhang Y, Sun Y.

TAMER 1.0 – Taxonomic Assignment of Metagenomic Sequencing Reads

TAMER 1.0

:: DESCRIPTION

TAMER is an R package for accurate taxonomic assignment of metagenomic sequencing reads.

::DEVELOPER

Lingling An , Hongmei Jiang

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows
  • R

:: DOWNLOAD

 TAMER

:: MORE INFORMATION

Citation

PLoS One. 2012;7(10):e46450. doi: 10.1371/journal.pone.0046450. Epub 2012 Oct 1.
A statistical framework for accurate taxonomic assignment of metagenomic sequencing reads.
Jiang H1, An L, Lin SM, Feng G, Qiu Y.

WhatsHap – Haplotype Assembly for Future-Generation Sequencing Reads

WhatsHap

:: DESCRIPTION

WhatsHap is a software for phasing genomic variants using DNA sequencing reads, also called haplotype assembly. It is especially suitable for long reads, but works also well with short reads.

::DEVELOPER

The Algorithms for Computational Genomics group 

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Python
  • C++

:: DOWNLOAD

 WhatsHap

:: MORE INFORMATION

Citation

WhatsHap: Weighted Haplotype Assembly for Future-Generation Sequencing Reads.
Patterson M, Marschall T, Pisanti N, van Iersel L, Stougie L, Klau GW, Schönhuth A.
J Comput Biol. 2015 Jun;22(6):498-509. doi: 10.1089/cmb.2014.0157

PgSA 1.2 – Index allowing Queries for a collection of Sequencing Reads

PgSA 1.2

:: DESCRIPTION

PgSA (Pseudogenome Suffix Array) is a compact index for collections of reads from sequencing. It allows to ask for presence of k-mers in the reads.

::DEVELOPER

REFRESH Bioinformatics Group

:: SCREENSHOTS

n/a

:: REQUIREMENTS

  • Linux
  • C++ Compiler

:: DOWNLOAD

 PgSA

:: MORE INFORMATION

Citation

PLoS One. 2015 Jul 16;10(7):e0133198. doi: 10.1371/journal.pone.0133198. eCollection 2015.
Indexing Arbitrary-Length k-Mers in Sequencing Reads.
Kowalski T, Grabowski S, Deorowicz S.

GeneSeq 1.0 – LD-based Genotype Calling from Shotgun Sequencing Reads

GeneSeq 1.0

:: DESCRIPTION

GeneSeq package provides methods to call SNP genotypes and infer haplotypes for a single individual given reads produced by whole-genome shotgun sequencing using high-throughput technologies such as 454, Illumina, and ABI SOLiD.  GeneSeq yields high genotype calling accuracy even from low read coverage by ecploting linkage disequilibrium patterns extracted from a reference panel such as those generated by the international Hapmap project.  Genotype and haplotype inference is  performed efficiently using a hierarchical factorial hidden Markov model (HF-HMM) integrating allele coverage information extracted from read data with haplotype frequencies inferred from the reference panel.

::DEVELOPER

Bioinformatics Lab , Computer Science & Engineering Dept. University of Connecticut

:: SCREENSHOTS

Command Line

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

GeneSeq

:: MORE INFORMATION

J. Duitama and J. Kennedy and S. Dinakar and Y. Hernandez and Y. Wu and I.I. Mandoiu,
Linkage Disequilibrium Based Genotype Calling from Low-Coverage Shotgun Sequencing Reads,
BMC Bioinformatics 12(Suppl 1):S53, 2011

Exit mobile version