TAGster – Single or Multi-Population Tag SNPs Selection, Evaluation and Visualization

TAGster

:: DESCRIPTION

TAGster is a tool to select, evaluate and visualize LD tag SNPs for single or multiple populations

::DEVELOPER

Jack A. Taylor, M.D., Ph.D. , Zongli Xu, Ph.D.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows /MacOsX

:: DOWNLOAD

 TAGster

:: MORE INFORMATION

Citation:

Xu Z, Kaplan NL, Taylor JA.
TAGster: efficient selection of LD tag SNPs in single or multiple populations.
Bioinformatics. 2007 23:3254-5. Epub 2007 Sep 7

SelSim 2.1 – Simulate Population Genetic Data with Selection and Recombination

SelSim 2.1

:: DESCRIPTION

SelSim is a program for Monte Carlo simulation of DNA polymorphism data for a recombining region within which a single bi-allelic site has experienced natural selection. SelSim allows simulation from either a fully stochastic model of, or deterministic approximations to, natural selection within a coalescent framework. A number of different mutation models are available for simulating surrounding neutral variation. The package enables a detailed exploration of the effects of different models and strengths of selection on patterns of diversity.

::DEVELOPER

Chris C A Spencer

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/WIndows

:: DOWNLOAD

 SelSim

:: MORE INFORMATION

Citation

Spencer C., Coop, G. (2005)
SelSim: A program to simulate population genetic data with selection and recombination.
Bioinformatics. 2004 Dec 12;20(18):3673-5.

OrthoSelect – Selection of Orthologs in Phylogenomics

OrthoSelect

:: DESCRIPTION

OrthoSelect is a easy-to-install and easy-to-use tool for finding ortholog groups in EST databases. It automatically searches assembled EST sequences against databases of ortholog groups (OG), assigns ESTs to these pre-defined OGs, translates the sequences into proteins, eliminates redundant sequences assigned to the same OG, creates multiple sequence alignments of identified ortholog sequences and others the possibility to further process this alignment in a last step. OrthoSelect performes better than the best-hit selection strategy and shows reliable results re-annotating database member sequences of OrthoMCL-DB and KOG. Since a correct orthology assignment is a important prerequisite for the construction of reliable data sets, OrthoSelect is capable of producing such data sets. This makes a OrthoSelect a valuable tool for researcher dealing with large EST libraries focussing on constructing data sets for phylogenetic reconstructions.

::DEVELOPER

the Department of Bioinformatics of the University of Göttingen

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Mac OS X
  • Perl

:: DOWNLOAD

OrthoSelect

:: MORE INFORMATION

Citation

F. Schreiber, K. Pick, D. Erpenbeck, G. W?rheide, B. Morgenstern (2009)
OrthoSelect: a protocol for selecting orthologous groups in phylogenomics
BMC Bioinformatics 10, 219

Alexa Fluor® Selection Guide – Find the Perfect Alexa Fluor® Dye

Alexa Fluor® Selection Guide

:: DESCRIPTION

Alexa Fluor® Selection Guide widget is designed to provide you with a concise and informative set of criteria for choosing the optimal Alexa Fluor® dye for your antibody or protein labeling application. Each page in this guide highlights a different Alexa Fluor® dye by summarizing key spectral data, excitation sources, and relevant product offerings. Full excitation and emission spectra are included for each of the dyes.

::DEVELOPER

Invitrogen Corporation

:: SCREENSHOTS

:: REQUIREMENTS

:: DOWNLOAD

Alexa Fluor® Selection Guide

:: MORE INFORMATION

N/A

G-POT 1.0 / PRIMER-ILP 1.0 – Multiplex-PCR Primer Set Selection

G-POT 1.0 / PRIMER-ILP 1.0

:: DESCRIPTION

G-POT is a primer set selection tool that minimizes the number of primers needed to amplify a set of loci while ensuring that each locus is amplified by a pair of primers located within L basepairs of each other, where L is an input parameter.

PRIMER-ILP is a primer set selection tool that minimizes the number of primers needed to amplify a set of loci while ensuring that each locus is amplified by a pair of primers located within L basepairs of each other, where L is an input parameter. The code uses the mixed integer linear programming solver from the GNU Linear Programming Package (GLPK) to solve the IP problem created from the input target sequences.

::DEVELOPER

Bioinformatics Lab , Computer Science & Engineering Dept. University of Connecticut

:: SCREENSHOTS

Command Line

:: REQUIREMENTS

:: DOWNLOAD

G-POTPRIMER-ILP

:: MORE INFORMATION

Citation:

K.M. Konwar, I.I. Mandoiu, A.C. Russell, and A.A. Shvartsman.
Improved Algorithms for Multiplex PCR Primer Set Selection with Amplification Length Constraints,
Proc. 3rd Asia-Pacific Bioinformatics Conference (APBC), pp. 41-50, 2005.

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