Tag: Segregate

CNViewer 20111128 – Identification of Duplications, Insertions or LOH that Segregates with a Disease Phenotype

CNViewer 20111128

:: DESCRIPTION

CNViewer aids the identification of regions of abnormal copy number variation that segregates with a disease phenotype in small pedigree.

::DEVELOPER

Ian’s DNA@Leeds

:: SCREENSHOTS

CNViewer1

:: REQUIREMENTS

  • Windows
  • Microsoft .NET framework version 2.0 

:: DOWNLOAD

 CNViewer

:: MORE INFORMATION

Citation

PLoS One. 2012;7(8):e43466. doi: 10.1371/journal.pone.0043466. Epub 2012 Aug 17.
Rapid visualisation of microarray copy number data for the detection of structural variations linked to a disease phenotype.
Carr IM, Diggle CP, Khan K, Inglehearn C, McKibbin M, Bonthron DT, Markham AF, Anwar R, Dobbie A, Pena SD, Ali M.

TWINSIM – Simulate Twin-nuclear Families in which QTLs and Linked Markers are Segregating

TWINSIM

:: DESCRIPTION

TWINSIM generates nuclear families, a proportion of which contain monozygotic twins, in which multiple quantitative trait loci are segregating. One of these QTLs is linked to multiple markers. Families can be selected to contain high and/or low values at the quantitative or ordinal trait.

::DEVELOPER

David Duffy

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows /MacOsX /  Linux
  • Frotran 77

:: DOWNLOAD

 TWINSIM

:: MORE INFORMATION

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