SCHISM 1.1.3

:: DESCRIPTION

SCHISM is a computational tool designed to infer subclonal hierarchy and the tumor evolution from somatic mutations. The inference process involves computational assessment of two fundamental properties of tumor evolution: lineage precedence rule and lineage divergence rule.

::DEVELOPER

Karchin Lab

:: SCREENSHOTS

N/A

::REQUIREMENTS

• Linux
• Python

:: DOWNLOAD

SCHISM

:: MORE INFORMATION

Citation

Niknafs N, Beleva-Guthrie V, Naiman DQ, Karchin R.
SubClonal Hierarchy Inference from Somatic Mutations: Automatic Reconstruction of Cancer Evolutionary Trees from Multi-region Next Generation Sequencing.
PLoS Comput Biol. 2015 Oct 5;11(10):e1004416. doi: 10.1371/journal.pcbi.1004416. PMID: 26436540; PMCID: PMC4593588.