CT-Finder 20160513 / CRISPR-DT

:: DESCRIPTION

CT-Finder is a web service that allows a user to upload DNA sequences, set specifications according to experimental goals, and receive candidate guide RNA targets.

CRISPR-DT is a web application that allows a user to upload DNA sequences, set specifications according to experimental goals, and recieve target candidates. Optimal candidates are suggested through consideration of predicted target efficiency and off-target effect. A visualization of on- and off-target matches against the chosen reference genome is provided in JBrowse.

::DEVELOPER

Liang Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

• Linux
• C++ Compiler

:: DOWNLOAD

 CT-Finder

:: MORE INFORMATION

Citation

Zhu H, Liang C.
CRISPR-DT: designing gRNAs for the CRISPR-Cpf1 system with improved target efficiency and specificity.
Bioinformatics. 2019 Aug 15;35(16):2783-2789. doi: 10.1093/bioinformatics/bty1061. PMID: 30615056.

CT-Finder: A Web Service for CRISPR Optimal Target Prediction and Visualization.
Zhu H, Misel L, Graham M, Robinson ML, Liang C.
Sci Rep. 2016 May 23;6:25516. doi: 10.1038/srep25516.