EPIGPUHSIC 1.0 – Compute HSIC between all possible interaction of SNPs and a Quantitative Phenotype

EPIGPUHSIC 1.0

:: DESCRIPTION

EPIGPUHSIC is an approach to epistasis detection by exhaustive testing of all possible SNP pairs. The search strategy based on the Hilbert-Schmidt Independence Criterion can help delineate various forms of statistical dependence between the genetic markers and the phenotype.

::DEVELOPER

Bertram Mueller-Myhsok (bmm@mpipsykl.mpg.de) & Tony Kam-Thong [tony@mpipsykl.mpg.de],  Machine Learning and Computational Biology Research Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • R package
  • gputools R package
  • CUDA developer driver and Toolkit
  • GENABLE

:: DOWNLOAD

  EPIGPUHSIC

:: MORE INFORMATION

Citation

Bioinformatics. 2011 Jul 1;27(13):i214-21. doi: 10.1093/bioinformatics/btr218.
Epistasis detection on quantitative phenotypes by exhaustive enumeration using GPUs.
Kam-Thong T, Pütz B, Karbalai N, Müller-Myhsok B, Borgwardt K.