Tag: Promoter Analysis

Asap – Promoter Analysis

Asap

:: DESCRIPTION

Asap is an open source framework for promoter analysis based on a fast search engine using enhanced suffix arrays. The framework includes several statistics for calculating over-representation of motifs in a set of promoters from co-regulated genes compared to a background set.

::DEVELOPER

The Bioinformatics Centre , University of Copenhagen

:: SCREENSHOTS

asap

:: REQUIREMENTS

  • Linux/ MacOsX
  • Python

:: DOWNLOAD

 Asap

:: MORE INFORMATION

Citation:

Marstrand TT, Frellsen J, Moltke I, Thiim M, Valen E, Retelska D, Krogh A:
Asap: a framework for over-representation statistics for transcription factor binding sites.
PLoS ONE 2008, 3(2):e1623

ModuleMaster 1.1 – Identify Cis-regulatory Modules using Promoter Analysis and Microarray Expression data Regression

ModuleMaster 1.1

:: DESCRIPTION

ModuleMaster is a novel application for finding cis-regulatory modules (CRMs) in sets of co-expressed genes. The application comes with a newly developed method which not only considers transcription factor binding information but also multivariate functional relationships between regulators and target genes to improve the detection of CRMs. Given only the results of a microarray and a subsequent clustering experiment, the program includes all necessary data and algorithms to perform every step to find CRMs.

::DEVELOPER

the Center for Bioinformatics Tübingen (Zentrum für Bioinformatik Tübingen, ZBIT).

:: SCREENSHOTS

ModuleMaster

:: REQUIREMENTS

  • Linux/ WIndows/MacOsX
  • Java

:: DOWNLOAD

  ModuleMaster

:: MORE INFORMATION

Citation

Biosystems. 2010 Jan;99(1):79-81. doi: 10.1016/j.biosystems.2009.09.005. Epub 2009 Oct 9.
ModuleMaster: a new tool to decipher transcriptional regulatory networks.
Wrzodek C, Schröder A, Dräger A, Wanke D, Berendzen KW, Kronfeld M, Harter K, Zell A.