The GRC (Genome Reverse Compiler) is an annotation tool for prokaryotic genomes. Its name and philosophy are based on analogy with a high-level, programming language compiler.
Gecko is a further development of the original Gecko software. It allows for the systematic detection of gene cluster conservation in a large number of genomes. The enhancement over the original Gecko tool is the use of set-distance based gene cluster models that allow for the detection of gene clusters with diverse conservation patterns including gaps and missing genes in cluster occurrences. It is also tolerant of errors in gene homology assignment.
MED is a non-supervised prokaryotic gene prediction method which integrates MED2.0 and TriTISA, an iterative self-learning translation initiation site (TIS) prediction algorithm. As the update of MED2.0, MED 2.1 modifies the TIS model by replacing the previous one to TriTISA, which imoroves the prediction accuracies for both 3′ and 5′ ends.
COLOMBO is a software framework equipped with a GUI for the statistical analysis of sequences of a genome. It can be equipped with different plugins that actually perform the analysis. The current version of COLOMBO is supplied with SIGI-HMM, a tool for the prediction of Genomic Islands.
PGAAS is prokaryotic genome assembly assistant system. The approach upon which PGAAS is based is to confirm the order of contigs and fill gaps between contigs through peptide links obtained by searching each contig end with BLASTX against protein database.
OxyGene is an innovative platform that addresses exploration and comparative analysis of oxidative stress subsystems in prokaryotic whole genomes. OxyGene integrates an original annotation database, called OxyDB, holding thoroughly tested signatures and a new ontology for ab initio detection of ROS/RNS response genes. Data can be downloaded and viewed using an intuitive graphic user-friendly interface that contains tabular, graphical and text tools.
::DEVELOPER
B@SIC (Bioinformatics Applied to Stresses and Cellular Interactions)