ProCon 2.0 – Localization & Visualization of Protein Conservation

ProCon 2.0

:: DESCRIPTION

ProCon is tool for locating and visualization of evolutionary conservation in protein sequences. The method can identify three types of conservation: identity (type I), physicochemical similarity (II), and covariant conservation (III). The conservative sites of type I and II are located with entropy calculation and the third type is identified by calculation of mutual information. The interacting networks formed by covariant pairs can also be identified. All the three types of conservation can be visualized in a representative protein structure. The tool performs exhaustive analysis results of which can be used e.g. for identifying different types of conserved residues, studying protein-protein interactions, explaining consequences of disease-causing mutations and mutant design for protein engineering.

::DEVELOPER

ProCon Team

:: SCREENSHOTS

:: REQUIREMENTS

  • Windows / Mac
  • Java

:: DOWNLOAD

 ProCon

:: MORE INFORMATION

ProCon 0.9.804 – PROteomics CONversion tool

ProCon 0.9.804

:: DESCRIPTION

ProCon is a conversion tool written in Java for conversion of proteomics identification data into standard formats mzIdentML and Pride XML.

::DEVELOPER

Medizinisches Proteom-Center, Medical Bioinformatics

:: SCREENSHOTS

ProCon

:: REQUIREMENTS

  • Linux / Windows/ MacOsX
  • JRE

:: DOWNLOAD

 ProCon

:: MORE INFORMATION

Citation

ProCon – PROteomics CONversion tool.
Mayer G, Stephan C, Meyer HE, Kohl M, Marcus K, Eisenacher M.
J Proteomics. 2015 Nov 3;129:56-62. doi: 10.1016/j.jprot.2015.06.015.