ProBias/BIAS – Detect Compositional Bias in Biological Sequences

ProBias/BIAS

:: DESCRIPTION

BIAS: a novel sensitive method for the detection of user-defined compositional bias in biological sequences.
BIAS automatically searches a user-supplied protein sequence for segments that contain unusually dense clusters of user-specified amino acid types and computes analytical estimates of the statistical significance of each cluster. These estimates are based on the discrete scan statistics that allows one to detect segments that exhibit even subtle local deviations from the random independence model.

ProBias: a web-server for the identification of user-specified types of compositionally biased segments in protein sequences

::DEVELOPER

Igor B. Kuznetsov

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/MacOsX/Windows

:: DOWNLOAD

 BIAS

:: MORE INFORMATION

Citation

I.Kuznetsov and S.Hwang (2006)
A novel sensitive method for the detection of user-defined compositional bias in biological sequences.
Bioinformatics, 22(9):1055-1063

I.Kuznetsov (2008)
ProBias: a web-server for the identification of user-specified types of compositionally biased segments in protein sequences
Bioinformatics 24(13): 1534-1535