CHANCE 2.0 b / CHANCE-HT 20140522 – ChIP-seq Data Pre-processing software

CHANCE 2.0 b / CHANCE-HT 20140522

:: DESCRIPTION

CHANCE (ChIP-seq Analytics and Confidence Estimation) is a software for assessing the quality of ChIP-seq experiments and providing feedback for the optimization of ChIP and library generation protocols.

CHANCE-HT is a ChIP-seq pre-processing software that filters samples with weak IP-strength, identifies heavily biased control experiments and under sequenced samples, detects batch effects, and normalizes large ensembles of ChIP-seq datasets.CHANCE-HT uses a parallel processing approach to normalize and filter large collections of ChIP-seq datasets in tandem.

::DEVELOPER

Diaz Lab , Jun S. Song’s Research Group

:: SCREENSHOTS

CHANCE

:: REQUIREMENTS

  • Windows /Linux/ MacOsX

:: DOWNLOAD

 CHANCE

:: MORE INFORMATION

Citation

A. Diaz, A. Nellore, J.S. Song.
CHANCE: a comprehensive software for quality control and validation of ChIP-seq data,
Genome Biology 13:R98, (2012).

HIPPO 1.5.0 – Heterogeneity Inspired pre-processing Tool

HIPPO 1.5.0

:: DESCRIPTION

HIPPO is a novel framework that leverages zero proportions to explain cellular heterogeneity and integrates feature selection with iterative clustering.

::DEVELOPER

Chen Group at U Chicago

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux /  Windows / MacOsX

:: DOWNLOAD

HIPPO

:: MORE INFORMATION

Citation

Kim TH, Zhou X, Chen M.
Demystifying “drop-outs” in single-cell UMI data.
Genome Biol. 2020 Aug 6;21(1):196. doi: 10.1186/s13059-020-02096-y. PMID: 32762710; PMCID: PMC7412673.