POLYPHEN 2.2.3 – Prediction of Functional Effects of Human nsSNPs

POLYPHEN 2.2.3

:: DESCRIPTION

PolyPhen (Polymorphism Phenotyping) is a tool which predicts possible impact of an amino acid substitution on the structure and function of a human protein using straightforward physical and comparative considerations.

::DEVELOPER

SUNYAEV LAB

:: SCREENSHOTS

N/A

::REQUIREMENTS

  • Linux / Windows / MacOsX
  • Perl

:: DOWNLOAD

 POLYPHEN

:: MORE INFORMATION

Citation

Ivan A Adzhubei , Steffen Schmidt , Leonid Peshkin , Vasily E Ramensky , Anna Gerasimova , Peer Bork , Alexey S Kondrashov & Shamil R Sunyaev
A method and server for predicting damaging missense mutations
Nat Methods 7, 248-9 (2010)