TrioVis 20130409
:: DESCRIPTION
TrioVis is a visualisation tool developed to assist filtering on coverage and variant frequency for genomic variants from exome sequencing of parent-child trios. It organises the variant data by grouping each variant based on the laws of Mendelian inheritance. Taking three Variant Call Format (VCF) files as input, the tool provides a user interface to test different coverage thresholds (i.e. different levels of stringency), to find the optimal threshold values, and to gain insights into the global effects of filtering.
::DEVELOPER
Bioinformatics Research Group, Belgium
:: SCREENSHOTS
:: REQUIREMENTS
- Linux / Windows / MacOsX
- Java
:: DOWNLOAD
:: MORE INFORMATION
Citation
Bioinformatics. 2013 Jul 15;29(14):1801-2. doi: 10.1093/bioinformatics/btt267. Epub 2013 May 8.
TrioVis: a visualization approach for filtering genomic variants of parent-child trios.
Sakai R, Sifrim A, Vande Moere A, Aerts J.