Tag: Pancreatic Cancer

DiPCell – Designing of Inhibitors against Pancreatic Cancer Cell Lines

DiPCell

:: DESCRIPTION

DiPCell is a webserver for the predicting inhibitory activity of unknown molecules and designing their analogs against pancreatic cancer cell lines. DiPCell implements the QSAR models, which were developed by using SMOreg machine learning algorithm on high throughput drug screening data. This high throughput screening data is obtained from the Genomics of Drug Sensitivity in Cancer (GDSC) database.

::DEVELOPER

DiPCell team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

Designing of promiscuous inhibitors against pancreatic cancer cell lines.
Kumar R, Chaudhary K, Singla D, Gautam A, Raghava GP.
Sci Rep. 2014 Apr 14;4:4668. doi: 10.1038/srep04668.

PCMdb – Pancreatic Cancer Methylation Database

PCMdb

:: DESCRIPTION

PCMdb is a database of methylated genes found in pancreatic cancer cell lines and tissues. In other words, it provides comprehensive information about methylation status of various genes in Pancreatic Cancer (PCa) and their comparison with transcriptomics and genomics landscape. It is a manually curated database where information is collected and compiled from literature/databases. This database will be very useful to discover novel biomakers for PCa as well as to understand the role of methylation in drug resistance.

::DEVELOPER

PCMdb team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

  NO

:: MORE INFORMATION

Citation

PCMdb: pancreatic cancer methylation database.
Nagpal G, Sharma M, Kumar S, Chaudhary K, Gupta S, Gautam A, Raghava GP.
Sci Rep. 2014 Feb 26;4:4197. doi: 10.1038/srep04197.