MoSeC 1.2 – Conversion of Dynamic Models of Complex Genetic Circuits into Nucleotide Sequences Ready for Synthesising

MoSeC 1.2

:: DESCRIPTION

MoSeC (Model to Sequence Converter) is a Java application for synthetic biology design that takes a model annotated with the DNA sequence information of genetic elements and converts it into a DNA sequence.

::DEVELOPER

Interdisciplinary Computing and Complex BioSystems (ICOS) research group

:: SCREENSHOTS

MoSeC

:: REQUIREMENTS

  • Linux / Windows/ MacOsX
  • JRE

:: DOWNLOAD

 MoSeC

:: MORE INFORMATION

Citation

Bioinformatics. 2011 Apr 1;27(7):973-9. doi: 10.1093/bioinformatics/btr048. Epub 2011 Feb 4.
Model annotation for synthetic biology: automating model to nucleotide sequence conversion.
Misirli G, Hallinan JS, Yu T, Lawson JR, Wimalaratne SM, Cooling MT, Wipat A.

XXmotif 1.6 – eXhaustive, weight matriX-based Motif Discovery in Nucleotide Sequences

XXmotif 1.6

:: DESCRIPTION

The XXmotif web server can discover motifs that are enriched in sets of nucleotide sequences provided by the user. XXmotif uses a new approach for finding enriched motifs: It directly optimizes the statistical significance of enrichment for PWMs. It can also score conservation and positional clustering of motifs. In several benchmarks on yeast and metazoan sequences, the underlying XXmotif method showed better sensitivity and produced PWMs of higher quality than state-of-the-art tools.

::DEVELOPER

Söding Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOsX
  • Perl

:: DOWNLOAD

 XXmotif

:: MORE INFORMATION

Citation:

Nucleic Acids Res. 2012 Jul;40(Web Server issue):W104-9. doi: 10.1093/nar/gks602. Epub 2012 Jun 12.
The XXmotif web server for eXhaustive, weight matriX-based motif discovery in nucleotide sequences.
Luehr S, Hartmann H, Söding J.

LDDist 1.3.2 – Calculating LogDet Pair-wise Distances for Protein and Nucleotide Sequences

LDDist 1.3.2

:: DESCRIPTION

LDDist is a Perl module implemente in C++ that enables the user to calculate LogDet pair-wise genetic distances based on amino acid as well as DNA/RNA sequences

::DEVELOPER

Mikael Thollesson

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/MacOsX/ Windows
  • Perl
  • C++ Compiler

:: DOWNLOAD

 LDDist

:: MORE INFORMATION

Citation

Bioinformatics. 2004 Feb 12;20(3):416-8. Epub 2004 Jan 22.
LDDist: a Perl module for calculating LogDet pair-wise distances for protein and nucleotide sequences.
Thollesson M.