NICE – Next-generation Intersample Correlation Emended

NICE

:: DESCRIPTION

NICE is a statistical test for correcting for expression heterogeneity inherent in expression dataset due to confounding from unmodeled factors. NICE estimates inter-sample correlation structure using only the genes with confounding effects and incorporates it as signatures of the systematic confounding effects to correct for it.

:: DEVELOPER

NICE team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / WIndows /MacOsX
  • R
  • Java

:: DOWNLOAD

 NICE

:: MORE INFORMATION

Citation

Joo JW, Sul JH, Han B, Ye C, Eskin E.
Effectively identifying regulatory hotspots while capturing expression heterogeneity in gene expression studies,
Genome Biology, 15:r61, 2014.