NetMHCIIpan 3.2 – predict Pan-specific Binding of Peptides to MHC class II HLA-DR Alleles

NetMHCIIpan 3.2

:: DESCRIPTION

NetMHCIIpan predicts binding of peptides to more than 500 HLA-DR alleles using artificial neural networks (ANNs). The prediction values are given in nM IC50 values and as %-Rank to a set of 200.000 random natural peptides.

::DEVELOPER

DTU Health Tech

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

NetMHCIIpan

:: MORE INFORMATION

Citation

Accurate pan-specific prediction of peptide-MHC class II binding affinity with improved binding core identification.
Andreatta M, Karosiene E, Rasmussen M, Stryhn A, Buus S, Nielsen M.
Immunogenetics. 2015 Sep 29.

NetMHCIIpan-3.0, a common pan-specific MHC class II prediction method including all three human MHC class II isotypes, HLA-DR, HLA-DP and HLA-DQ
Karosiene E, Rasmussen M, Blicher T, Lund O, Buus S, and Nielsen M
Immunogenetics, 2013

NetMHCIIpan-2.0 – Improved pan-specific HLA-DR predictions using a novel concurrent alignment and weight optimization training procedure
Nielsen M1, Lundegaard C1, Justesen S2, Lund O1, and Buus S2
Immunome Res. 2010 Nov 13;6(1):9.