NBC – Naive Bayes Classification tool

NBC

:: DESCRIPTION

NBC uses a method similar to that used in many email spam filters to score a genetic sample against different genomes, to possibly identify the closest match.

::DEVELOPER

Drexel’s EESI Lab.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

Linux

:: DOWNLOAD

NBC

:: MORE INFORMATION

Citation

NBC: the Naive Bayes Classification tool webserver for taxonomic classification of metagenomic reads.
Rosen GL, Reichenberger ER, Rosenfeld AM.
Bioinformatics. 2011 Jan 1;27(1):127-9. doi: 10.1093/bioinformatics/btq619.

NBC update: The addition of viral and fungal databases to the Naïve Bayes classification tool.
Rosen GL, Lim TY.
BMC Res Notes. 2012 Jan 31;5:81. doi: 10.1186/1756-0500-5-81.

NBC 1.0 – Neighborhood Breakpoint Conservation

NBC 1.0

:: DESCRIPTION

NBC (Neighborhood Breakpoint Conservation) is a method that identifies recurrent copy number variants in multiple individuals using Array Comparative Genomic Hybridization (aCGH).aCGH computes the ratio of test:reference DNA for probes located on the reference genome. NBC first uses a Bayesian changepoint algorithm to identify probes, called breakpoints, that change from low-to-high or high-to-low copy number with high probability. A binomial statistic is then applied to identify breakpoints and pairs of breakpoints that appear in a statistically significant number of individuals.

::DEVELOPER

Raphael Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

Linux/MacOsx/WIndows
Java

:: DOWNLOAD

NBC

:: MORE INFORMATION

Citation

A. Ritz, P.L. Paris, M.M. Ittmann, C. Collins, and B.J. Raphael. (2011)
Detection of Recurrent Rearrangement Breakpoints from Copy Number Data.
BMC Bioinformatics 2011, 12:114 doi:10.1186/1471-2105-12-114