Multi-Dendrix 1.0 – Multiple Pathway De novo Driver Exclusivity

Multi-Dendrix 1.0

:: DESCRIPTION

Multi-Dendrix is an algorithm for the simultaneous discovery of multiple driver pathways using only somatic mutation data from a cohort of samples. Multi-Dendrix uses an integer linear program to identify pathway sets such that each pathway contains genes with approximately mutually exclusive mutations and high coverage of the sample set.

::DEVELOPER

Raphael Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Python

:: DOWNLOAD

   Multi-Dendrix

:: MORE INFORMATION

Citation:

M.D.M. Leiserson, D. Blokh, R. Sharan, B.J. Raphael. (2013)
Simultaneous Identification of Multiple Driver Pathways in Cancer.
PLoS Comp Bio, 9(5):e1003054