MOAT v1.0

:: DESCRIPTION

MOAT is a computational system for identifying significant mutation burdens in genomic elements with an empirical, nonparametric method. Taking a set of variant calls and a set of annotations, MOAT calculates which annotations have observed variant counts that are substantially elevated with respect to a distribution of expected variant counts determined by permutation of the input data.

::DEVELOPER

Gerstein Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

• Linux

:: DOWNLOAD

MOAT 

:: MORE INFORMATION

Citation:

Bioinformatics. 2018 Mar 15;34(6):1031-1033. doi: 10.1093/bioinformatics/btx700.
MOAT: efficient detection of highly mutated regions with the Mutations Overburdening Annotations Tool.
Lochovsky L, Zhang J, Gerstein M.