miRNA Digger – Genome-wide novel miRNA Mining

miRNA Digger

:: DESCRIPTION

miRNA Digger is a pipeline for large-scale identifiction of the new microRNA genes by screening the cleavage signals resided within the genome.

::DEVELOPER

miRNA Digger team

:: SCREENSHOTS

miRNADigger

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

 miRNA Digger

:: MORE INFORMATION

Citation:

miRNA Digger: a comprehensive pipeline for genome-wide novel miRNA mining.
Yu L, Shao C, Ye X, Meng Y, Zhou Y, Chen M.
Sci Rep. 2016 Jan 6;6:18901. doi: 10.1038/srep18901.

GemiNI – Network based integration of Gene Expression profiles with miRNA Expression Profiles

GemiNI

:: DESCRIPTION

GemiNI /dChip-GemiNi (Gene and miRNA Network-based Integration) is a web server which is an integrative analysis of gene and miRNA expression profiles with transcription factor-miRNA feed-forward loops

::DEVELOPER

Mehmet Kemal Samur

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 GemiNI

:: MORE INFORMATION

Citation

Nucleic Acids Res. 2012 Sep 1;40(17):e135.
Integrative analysis of gene and miRNA expression profiles with transcription factor-miRNA feed-forward loops identifies regulators in human cancers.
Yan Z, Shah PK, Amin SB, Samur MK, Huang N, Wang X, Misra V, Ji H, Gabuzda D, Li C.

mirConnX – Analysis of mRNA and microRNA (miRNA) Gene Regulatory Networks

mirConnX

:: DESCRIPTION

mirConnX is a user-friendly web interface for inferring, displaying and parsing mRNA and microRNA (miRNA) gene regulatory networks. mirConnX combines sequence information, and computational predictions with gene expression data analysis to create a disease-specific, genome-wide regulatory network.

::DEVELOPER

Benos Lab

 SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

Nucleic Acids Res. 2011 Jul;39(Web Server issue):W416-23. doi: 10.1093/nar/gkr276. Epub 2011 May 10.
mirConnX: condition-specific mRNA-microRNA network integrator.
Huang GT, Athanassiou C, Benos PV.

MIRPIPE 1.2.1 – miRNA detection and quantification pipeline

MIRPIPE 1.2.1

:: DESCRIPTION

MIRPIPE enables rapid and simple browser-based miRNA homology detection and quantification.

::DEVELOPER

the Loosolab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Perl

:: DOWNLOAD

 MIRPIPE

:: MORE INFORMATION

Citation:

MIRPIPE – quantification of microRNAs in niche model organisms.
Kuenne C, Preussner J, Herzog M, Braun T, Looso M.
Bioinformatics. 2014 Aug 26. pii: btu573.

CCmiR – Prediction of miRNA Competitive / Cooperative Binding

CCmiR

:: DESCRIPTION

CCmiR is a software for competitive and cooperative microRNA binding prediction

::DEVELOPER

Hu Lab – Data Integration and Knowledge Discovery @ UCF

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows

:: DOWNLOAD

CCmiR

:: MORE INFORMATION

Citation:

Bioinformatics. 2018 Jan 15;34(2):198-206. doi: 10.1093/bioinformatics/btx606.
CCmiR: a computational approach for competitive and cooperative microRNA binding prediction.
Ding J, Li X, Hu H.

MITHrIL 1.0 – Mirna enrIched paTHway Impact anaLysis

MITHrIL 1.0

:: DESCRIPTION

MITHrIL (Mirna enrIched paTHway Impact anaLysis) is an algorithm developed for the analysis of signaling pathways. It extends pathways by adding missing regulatory elements, such as microRNAs, and their interactions with genes.

::DEVELOPER

MITHrIL team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows
  • Java

:: DOWNLOAD

MITHrIL

:: MORE INFORMATION

Citation:

Oncotarget. 2016 Aug 23;7(34):54572-54582. doi: 10.18632/oncotarget.9788.
Post-transcriptional knowledge in pathway analysis increases the accuracy of phenotypes classification.
Alaimo S, Giugno R, Acunzo M, Veneziano D, Ferro A, Pulvirenti A.

SplamiR – Predicting miRNAs in Plants

SplamiR

:: DESCRIPTION

SplamiR is the first method for the prediction of spliced miRNAs in plants. It takes genomic sequence and the sequence of a potential target mRNA as input. In the first phase of SplamiR, a database of complementary sequence pairs is created for the given genomic sequence. These sequence pairs might encode for RNAs folding into stem-loop structures. In the second phase, this database is searched for sequences with complementarity to the given target mRNA. For the identified sequences, in silico splice variants are generated and these are classified as to whether they might represent pre-miRNAs.

::DEVELOPER

Theißen lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Java

:: DOWNLOAD

  SplamiR

:: MORE INFORMATION

Citation:

Bioinformatics. 2011 May 1;27(9):1215-23. doi: 10.1093/bioinformatics/btr132. Epub 2011 Mar 17.
SplamiR–prediction of spliced miRNAs in plants.
Thieme CJ, Gramzow L, Lobbes D, Theissen G.

miFRame – Analysis and Visualization of miRNA sequencing data in Neurological Disorders

miFRame

:: DESCRIPTION

miFRame which supports the analysis of human small RNA NGS data is a web server for analysis and visualization of miRNA sequencing data in neurological disorders.

::DEVELOPER

Chair for clinical bioinformatics

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation:

J Transl Med. 2015 Jul 14;13:224. doi: 10.1186/s12967-015-0594-x.
miFRame: analysis and visualization of miRNA sequencing data in neurological disorders.
Backes C, Haas J, Leidinger P, Frese K, Großmann T, Ruprecht K, Meder B, Meese E, Keller A

MiRCat 1.2 – miRNA Sequence Profiling

MiRCat 1.2

:: DESCRIPTION

MiRCat is a revolutionary new way of sharing and analysing sequencing data for small RNA.

::DEVELOPER

Victor Chang Cardiac Research Institute

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Perl

:: DOWNLOAD

 MiRCat

:: MORE INFORMATION

Citation:

Nucleic Acids Res. 2013 Aug 1;41(15):e147. doi: 10.1093/nar/gkt485. Epub 2013 Jun 17.
miRspring: a compact standalone research tool for analyzing miRNA-seq data.
Humphreys DT, Suter CM.

MirCheck – Identify Plant miRNA Genes

MirCheck

:: DESCRIPTION

MIRcheck is a perl script designed to identify RNA sequences with secondary structures similar to plant miRNAs.  It compares a potential miRNA and precursor against a set of secondary structure constraints derived from known plant miRNA precursors.  The potential miRNA and precursor “pass” MIRcheck if all requirements are met, and “fail” MIRcheck if one or more is not.

::DEVELOPER

Bartel Lab at Whitehead Institute for Biomedical Research

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/ Windows/MacOsX
  • perl

:: DOWNLOAD

 MirCheck

:: MORE INFORMATION

Citation

Mol Cell. 2004 Jun 18;14(6):787-99.
Computational identification of plant microRNAs and their targets, including a stress-induced miRNA.
Jones-Rhoades MW, Bartel DP.