DRME – Differential RNA Methylation Analysis

DRME

:: DESCRIPTION

DRME is an R package of count-based differential RNA methylation analysis at small sample size scenario.

::DEVELOPER

DRME team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / Linux/ MacOsX
  • R

:: DOWNLOAD

 DRME

:: MORE INFORMATION

Citation

DRME: Count-based differential RNA methylation analysis at small sample size scenario.
Liu L, Zhang SW, Gao F, Zhang Y, Huang Y, Chen R, Meng J.
Anal Biochem. 2016 Feb 4;499:15-23. doi: 10.1016/j.ab.2016.01.014

SRAMP – Sequence-based RNA Adenosine Methylation Site Predictor

SRAMP

:: DESCRIPTION

SRAMP would serve as a useful tool to predict m6A modification sites on the RNA sequences

::DEVELOPER

the Cui Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

SRAMP

:: MORE INFORMATION

Citation

SRAMP: prediction of mammalian N6-methyladenosine (m6A) sites based on sequence-derived features.
Zhou Y, Zeng P, Li YH, Zhang Z, Cui Q.
Nucleic Acids Res. 2016 Feb 20. pii: gkw104.

RADAR v0.2.4 – Differential Methylation analysis for m6A Sequence data

RADAR v0.2.4

:: DESCRIPTION

RADAR is a comprehensive analytical tool for detecting differentially methylated loci in MeRIP-seq data.

::DEVELOPER

Chen Group at U Chicago

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux /  Windows / MacOsX

:: DOWNLOAD

RADAR

:: MORE INFORMATION

Citation

Zhang Z, Zhan Q, Eckert M, Zhu A, Chryplewicz A, De Jesus DF, Ren D, Kulkarni RN, Lengyel E, He C, Chen M.
RADAR: differential analysis of MeRIP-seq data with a random effect model.
Genome Biol. 2019 Dec 23;20(1):294. doi: 10.1186/s13059-019-1915-9. PMID: 31870409; PMCID: PMC6927177.

CNAmet 1.2.1 – Integrate Copy Number, Methylation and Expression data

CNAmet 1.2.1

:: DESCRIPTION

CNAmet is an algorithm and R package that facilitates the integration of copy number, methylation and expression data. In addition to the CNAmet algorithm, the R package includes the S2N algorithm for the integration of copy number to expression data.

::DEVELOPER

Hautaniemi Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/Linux/MacOsX
  • R Package

:: DOWNLOAD

 CNAmet

:: MORE INFORMATION

Citation

CNAmet: an R package for integrating copy number, methylation and expression data
Riku Louhimo and Sampsa Hautaniemi
Bioinformatics (2011) 27 (6): 887-888.

SeSAMe 1.11.0 – SEnsible Step-wise Analysis of Methylation data

SeSAMe 1.11.0

:: DESCRIPTION

SeSAMe is an R package for processing Infinium DNA methylation data. SeSAMe currently supports EPIC, HM450 and HM27 platforms and dynamically generated manifest.

::DEVELOPER

Zhou lab

:: SCREENSHOTS

N/A

::  REQUIREMENTS

  • Linux / Windows / MacOs
  • R
  • BioConductor

:: DOWNLOAD

SeSAMe

:: MORE INFORMATION

Citation

Zhou W, Triche TJ Jr, Laird PW, Shen H.
SeSAMe: reducing artifactual detection of DNA methylation by Infinium BeadChips in genomic deletions.
Nucleic Acids Res. 2018 Nov 16;46(20):e123. doi: 10.1093/nar/gky691. PMID: 30085201; PMCID: PMC6237738.

methylFlow 0.1.0-Pre – Cell-specific Methylation Pattern Reconstruction

methylFlow 0.1.0-Pre

:: DESCRIPTION

methylFlow is a software of cell-specific methylation pattern reconstruction from high-throughput bisulfite-converted DNA sequencing.

::DEVELOPER

HCBravo Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 methylFlow

:: MORE INFORMATION

Citation

methylFlow: cell-specific methylation pattern reconstruction from high-throughput bisulfite-converted DNA sequencing.
Dorri F, Mendelowitz L, Corrada Bravo H.
Bioinformatics. 2016 Jun 1;32(11):1618-24. doi: 10.1093/bioinformatics/btw287

FadE 0.0.2 – DNA Methylation Detection

FadE 0.0.2

:: DESCRIPTION

FadE is a software package which was designed to determine the methylation parameter at each cytosine or cytosine-guanine position in the human genome. FadE uses color reads produced by the SOLiD sequencer.

::DEVELOPER

Ting Chen

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • C++ Compiler

:: DOWNLOAD

 FadE

:: MORE INFORMATION

Citation

Nucleic Acids Res. 2013 Jan 7;41(1):e14. doi: 10.1093/nar/gks830. Epub 2012 Sep 10.
FadE: whole genome methylation analysis for multiple sequencing platforms.
Souaiaia T1, Zhang Z, Chen T.

Methpat 2.0.0 – A program for Summarising CpG Methylation Patterns

Methpat 2.0.0

:: DESCRIPTION

Methpat summarises the resultant DNA methylation pattern data from the output of Bismark bismark_methylation_extractor.

::DEVELOPER

Bernie Pope

: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/ Windows/MacOsX
  • Python
  • Bismark v0.12.2 and it’s dependencies (bwa v0.7.5a-r405).

:: DOWNLOAD

 Methpat

:: MORE INFORMATION

Citation

MethPat: a tool for the analysis and visualisation of complex methylation patterns obtained by massively parallel sequencing.
Wong NC, Pope BJ, Candiloro IL, Korbie D, Trau M, Wong SQ, Mikeska T, Zhang X, Pitman M, Eggers S, Doyle SR, Dobrovic A.
BMC Bioinformatics. 2016 Feb 24;17(1):98. doi: 10.1186/s12859-016-0950-8.

epiPaleomix – Inference of Ancient DNA Methylation and Nucleosomal Positioning

epiPaleomix

:: DESCRIPTION

epiPaleomix is a Fast, Accurate, and Automatic pipeline for generating nucleosome and methylation maps from high throughput sequencing data underlying ancient samples.

::DEVELOPER

The Centre for Anthropobiology and Genomics of Toulouse

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

epiPaleomix

:: MORE INFORMATION

Citation

Hanghoj K, Seguin-Orlando A, Schubert M, Madsen T, Pedersen JS, Willerslev E, Orlando L.
Fast, Accurate and Automatic Ancient Nucleosome and Methylation Maps with epiPALEOMIX.
Mol Biol Evol. 2016 Dec;33(12):3284-3298. doi: 10.1093/molbev/msw184. Epub 2016 Sep 13. PMID: 27624717; PMCID: PMC5100044.

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