LocNES – Locating Classical NESs in CRM1 Cargo Proteins

LocNES

:: DESCRIPTION

LocNES (Locating Nuclear Export Signals or NESs) is a Support Vector Machine (SVM) predictor that locates classical nuclear export signals (NESs) in CRM1 cargoes. Export-Karyopherinβ CRM1 recognizes hundreds of broadly functioning proteins. Most CRM1 cargoes contain the classical NES (also known as leucine-rich NESs), a peptide with 8-15 amino acids, regularly spaced with conserved hydrophobic residues.

::DEVELOPER

Chook Lab,UT Southwestern Medical Center

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

LocNES: A computational tool for locating classical NESs in CRM1 cargo proteins.
Xu D, Marquis K, Pei J, Fu SC, Cağatay T, Grishin NV, Chook YM.
Bioinformatics. 2014 Dec 15. pii: btu826.