Tag: INTeractome

DTome – Drug-Target Interactome

DTome

:: DESCRIPTION

DTome provides a computational framework to effectively construct a drug-target networks by integrating the drug-drug interactions, drug-target interactions, drug-gene associations and target/gene-protein interactions.

::DEVELOPER

Bioinformatics and Systems Medicine Laboratory,

:: SCREENSHOTS

n/a

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation:

DTome: a web-based tool for drug-target interactome construction.
Sun J, Wu Y, Xu H, Zhao Z.
BMC Bioinformatics. 2012 Jun 11;13 Suppl 9:S7. doi: 10.1186/1471-2105-13-S9-S7.

InteractoMIX – Exploit Interactomes in Biological and Clinical Research

InteractoMIX

:: DESCRIPTION

InteractoMIX is a suite of computational tools designed to exploit interactomics information at different levels ranging from genome-wide interactomes to their atomic 3D structural details.

::DEVELOPER

 Bioinformatics Lab :: IBERS :: Aberystwyth University

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Server

:: DOWNLOAD

  NO

:: MORE INFORMATION

Citation

Biochem Soc Trans, 44 (3), 917-24 2016 Jun 15
InteractoMIX: A Suite of Computational Tools to Exploit Interactomes in Biological and Clinical Research
Daniel Poglayen et al.

SAINT 3.6.3 – Significance Analysis of INTeractome

SAINT 3.6.3

:: DESCRIPTION

SAINT (Significance Analysis of Interactome) is a software for filtering high confidence interactions from spectral count data in affinity purification–mass spectrometry.

::DEVELOPER

Proteomics & Integrative Bioinformatics Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOsX
  • C Compiler

:: DOWNLOAD

  SAINT

:: MORE INFORMATION

Citation:

H. Choi et al (2010),
SAINT: probabilistic scoring of affinity purification–mass spectrometry data
Nature Methods 8, 70–73 (2011)

APID2NET – Unified Interactome Graphic Analyzer

APID2NET

:: DESCRIPTION

APID2NET is an open access tool, included in Cytoscape, that allows to surf unified interactome data by quering APID server and facilitates dynamic analysis of the protein-protein interaction (PPI) networks. The program is designed to visualize, dynamically explore and analyze the proteins and interactions retrieved, including all the annotations and attributes associated to such PPIs, i.e.: GO terms, Pfam and InterPro domains, experimental methods that validate each interaction, PubMed IDs, UniProt IDs, etc. The tool provides a rich interactive graphical representation of the networks with all Cytoscape capabilities, plus new automatic tools to find and locate concurrent functional and structural attributes along all protein pairs in a network. A hubs location tool is also implemented.

::DEVELOPER

 APID2NET Team

:: SCREENSHOTS

:: REQUIREMENTS

:: DOWNLOAD

   APID2NET

:: MORE INFORMATION

Citation

Hernandez-Toro J., Prieto C. and De Las Rivas J. (2007).
APID2NET: unified interactome graphic analyzer.
Bioinformatics 23(18): 2495-2497. PMID: 17644818.