Tag: Insight

INSIGHT 1.1 – Inference of Natural Selection from Interspersed Genomically coHerent elemenTs

INSIGHT 1.1

:: DESCRIPTION

INSIGHT is a method for inferring signatures of recent natural selection from patterns of polymorphism and divergence across a collection of short dispersed genomic elements.

::DEVELOPER

Siepel Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

INSIGHT

 :: MORE INFORMATION

Citation

Gronau I, Arbiza L, Mohammed J, Siepel A.
Inference of natural selection from interspersed genomic elements based on polymorphism and divergence.
Mol Biol Evol. 2013 May;30(5):1159-71. doi: 10.1093/molbev/mst019. Epub 2013 Feb 5. PMID: 23386628; PMCID: PMC3697874.

CluePedia 1.0.5 – Provide Insights into Pathways by integrating Experimental and in silico Information

CluePedia 1.0.5

:: DESCRIPTION

CluePedia provides a holistic view on a pathway or process by investigating experimental and in silico data from different perspectives: gene interrelations revealed by correlation weights, miRNAs regulatory aspects, protein – protein interactions as well as the functional context, in conjunction with ClueGO. This review is helpful for defining new hypothesis and strategies that allow one more step in understanding complex processes.

::DEVELOPER

Integrative Cancer Immunology Laboratory

:: SCREENSHOTS

CluePedia

:: REQUIREMENTS

:: DOWNLOAD

 CluePedia

:: MORE INFORMATION

Citation

Bindea G, Galon J and Mlecnik B.
CluePedia Cytoscape plugin: pathway insights using integrated experimental and in silico data.
Bioinformatics. 2013 Mar 1;29(5):661-3.