Heritability Calculator – Compute Heritability for different Genetic Architectures

Heritability Calculator

:: DESCRIPTION

Heritability Calculator (HC) is a comprehensive package enabling the calculations of epidemiological and genetic parameters (such as broad/narrow sense heritabilities, true and population based heritability estimates, familial relative risk, marginal and epistatic effect size, detection power) for general (non-additive) genetic architectures.

::DEVELOPER

The Broad Institute, Cambridge, MA

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Mac OsX / Windows
  • Matlab

:: DOWNLOAD

 Heritability Calculator

:: MORE INFORMATION

Citation

The Mystery of Missing Heritability: Genetic Interactions Create Phantom Heritability 
O. Zuk, E. Hechter, S. Sunyaev and E.S. Lander
Proceedings of the National Academy of Science (2012) doi: 10.1073/pnas.1119675109

HEIDI 0.1 – Partition the total Heritability into the Contributions of Genomic Regions

HEIDI 0.1

:: DESCRIPTION

HEIDI (Heritability EstImations DIstributed) is a linear mixed model based approach to partition the total heritability into the contributions of genomic regions.

::DEVELOPER

ZarLab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 HEIDI

:: MORE INFORMATION

Citation

Am J Hum Genet. 2013 Apr 4;92(4):558-64. doi: 10.1016/j.ajhg.2013.03.010.
Improving the accuracy and efficiency of partitioning heritability into the contributions of genomic regions.
Kostem E, Eskin E.