thunder 0.10 – LD-based Genotype Caller and Haplotyper on Massively Parallel Sequencing data

thunder 0.10

:: DESCRIPTION

thunder is a LD-based genotype caller and haplotyper on massively parallel sequencing data

::DEVELOPER

Yun Li

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
:: DOWNLOAD

 thunder

:: MORE INFORMATION

Citation

Li Y, Sidore C, Kang HM, Boehnke M, Abecasis GR.
Low-coverage sequencing: Implications for design of complex trait association studies.
Genome Res. 2011 Jun;21(6):940-51.

Haplotyper 1.0 – Genotype Format Data from an Excel File to a Format of Arlequin

Haplotyper 1.0

:: DESCRIPTION

Haplotyper (Genotype Transposer) is an excel macro that will format data from an Excel spreadsheet to a format ready to be used by the program “Arlequin“, which will reconstruct haplotype frequencies within the population, based on the genotypes given.  After which, other macros will extract the haplotype information, calculate linkage disequilibrium between markers, and prepare an input sheet for the “GOLD” program, which makes a graphical display of this data.  Then, a last macro can reconstruct the haplotypes of each individual in the population, using a maximum likelihood method and the haplotypes present in the population as proposed by Arlequin.

::DEVELOPER

David G. Cox

:: SCREENSHOTS

:: REQUIREMENTS

  • EXCEL

:: DOWNLOAD

Haplotyper

:: MORE INFORMATION

haplotyper has evolved into PHARE

 

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