Tag: GRAM

GRAM 0.6 – Discovery of Gene Modules and Regulatory Networks

GRAM 0.6

:: DESCRIPTION

GRAM (Genetic RegulAtory Modules) identifies modules, collections of genes that share common regulators as well as expression profiles.

::DEVELOPER

the Gifford Laboratory

:: SCREENSHOTS

:: REQUIREMENTS

  • Linux/ Windows/MacOsX
  • Java

:: DOWNLOAD

GRAM

:: MORE INFORMATION

Citation

Nat Biotechnol. 2003 Nov;21(11):1337-42. Epub 2003 Oct 12.
Computational discovery of gene modules and regulatory networks.
Bar-Joseph Z, Gerber GK, Lee TI, Rinaldi NJ, Yoo JY, Robert F, Gordon DB, Fraenkel E, Jaakkola TS, Young RA, Gifford DK.

GRAM – Predict Molecular Effect of Non-coding Variant in Cell Type-specific Manner

GRAM

:: DESCRIPTION

GRAM (GeneRAlized Model) combines a universal regulatory score defined by transcription factor binding with an easily obtainable modifier defined by transcription factor binding and expression to reflect the particular cell type.

::DEVELOPER

Gerstein Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

GRAM

:: MORE INFORMATION

Citation:

GRAM: A GeneRAlized Model to predict the molecular effect of a non-coding variant in a cell-type specific manner.
Lou S, Cotter KA, Li T, Liang J, Mohsen H, Liu J, Zhang J, Cohen S, Xu J, Yu H, Rubin MA, Gerstein M.
PLoS Genet. 2019 Aug 30;15(8):e1007860. doi: 10.1371/journal.pgen.1007860.

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