CRISPResso v2.2.6 – Analysis of Genome Editing Outcomes from Deep Sequencing data

CRISPResso v2.2.6

:: DESCRIPTION

CRISPResso2 is a software pipeline designed to enable rapid and intuitive interpretation of genome editing experiments.

::DEVELOPER

Pinello Lab.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

Linux/Windows/MacOsX
Python

:: DOWNLOAD

CRISPResso

:: MORE INFORMATION

Citation

Pinello L, et al.
Analyzing CRISPR genome-editing experiments with CRISPResso.
Nat Biotechnol, 34 (7), 695-7 2016 Jul 12

Clement K, et al.
CRISPResso2 provides accurate and rapid genome editing sequence analysis.
Nat Biotechnol. 2019 Mar; 37(3):224-226. doi: 10.1038/s41587-019-0032-3. PubMed PMID: 30809026.

GESTALT v1.0 – Genome Editing of Synthetic Target Arrays for Lineage Tracing

GESTALT v1.0

:: DESCRIPTION

GESTALT is a method that uses genome editing to progressively introduce and accumulate diverse mutations in a DNA barcode over multiple rounds of cell division, thereby recording cell lineage relationships in the patterns of mutations shared between cells.

::DEVELOPER

Shendure Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

Linux
R

:: DOWNLOAD

GESTALT

:: MORE INFORMATION

Citation

McKenna A, Findlay GM, Gagnon JA, Horwitz MS, Schier AF, Shendure J.
Whole-organism lineage tracing by combinatorial and cumulative genome editing.
Science. 2016 Jul 29;353(6298):aaf7907. doi: 10.1126/science.aaf7907. Epub 2016 May 26. PMID: 27229144; PMCID: PMC4967023.