Heritability Calculator – Compute Heritability for different Genetic Architectures

Heritability Calculator

:: DESCRIPTION

Heritability Calculator (HC) is a comprehensive package enabling the calculations of epidemiological and genetic parameters (such as broad/narrow sense heritabilities, true and population based heritability estimates, familial relative risk, marginal and epistatic effect size, detection power) for general (non-additive) genetic architectures.

::DEVELOPER

The Broad Institute, Cambridge, MA

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Mac OsX / Windows
  • Matlab

:: DOWNLOAD

 Heritability Calculator

:: MORE INFORMATION

Citation

The Mystery of Missing Heritability: Genetic Interactions Create Phantom Heritability 
O. Zuk, E. Hechter, S. Sunyaev and E.S. Lander
Proceedings of the National Academy of Science (2012) doi: 10.1073/pnas.1119675109

quantiNEMO 1.0.4 – Simulate Quantitative Traits with Explicit Genetic Architecture

quantiNEMO 1.0.4

:: DESCRIPTION

quantiNEMO is an individual-based program for the analysis of quantitative traits with explicit genetic architecture potentially under selection in a structured population. quantiNEMO was developed to investigate the effects of selection, mutation, recombination, and drift on quantitative traits with varying architectures in structured populations connected by migration and located in a heterogeneous habitat. quantiNEMO is highly flexible at various levels: population, selection, trait(s) architecture, genetic map for QTL and/or markers, environment, demography, mating system, etc.

::DEVELOPER

Samuel NeuenschwanderJérôme GoudetFrédéric Hospital, andFrédéric Guillaume.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / Linux / MacOS

:: DOWNLOAD

quantiNEMO

:: MORE INFORMATION

Citation

Neuenschwander S, Hospital F, Guillaume F, Goudet J (2008)
quantiNEMO: an individual-based program to simulate quantitative traits with explicit genetic architecture in a dynamic metapopulation
Bioinformatics 24, 1552-1553.