:: DESCRIPTION
HyDRA is a new approach to genomic data aggregation which combines the advantages of score-based and combinatorial aggregation techniques.
::DEVELOPER
Olgica Milenkovic’s Research Group
:: SCREENSHOTS
N/A
:: REQUIREMENTS
:: DOWNLOAD
:: MORE INFORMATION
Citation
HyDRA: Gene Prioritization via Hybrid Distance-Score Rank Aggregation.
Kim M, Farnoud F, Milenkovic O.
Bioinformatics. 2014 Nov 18. pii: btu766.
:: DESCRIPTION
PINTA is a gene prioritization tool that identifies the most promising candidates within a region when only sparse information about the phenotype is available by replacing this knowledge by experimental data on differential gene expression between affected and healthy individuals. Considering the problem from the perspective of a gene/protein network, it assesses the relevance of a candidate gene by considering the level of differential expression in its network neighborhood under the assumption that strong candidates tend to be surrounded by differentially expressed neighbors.
::DEVELOPER
Bioinformatics Research Group, Belgium
:: SCREENSHOTS
N/A
:: REQUIREMENTS
:: DOWNLOAD
NO
:: MORE INFORMATION
Citation
Nucleic Acids Res. 2011 Jul;39(Web Server issue):W334-8. doi: 10.1093/nar/gkr289. Epub 2011 May 20.
PINTA: a web server for network-based gene prioritization from expression data.
Nitsch D, Tranchevent LC, Gon?alves JP, Vogt JK, Madeira SC, Moreau Y.
:: DESCRIPTION
Phen2Gene is a phenotype-driven gene prioritization tool, that takes HPO (Human Phenotype Ontology) IDs as inputs, searches and prioritizes candidate causal disease genes.
::DEVELOPER
:: SCREENSHOTS
N/A
:: REQUIREMENTS
:: DOWNLOAD
:: MORE INFORMATION
Citation
Zhao M, Havrilla JM, Fang L, Chen Y, Peng J, Liu C, Wu C, Sarmady M, Botas P, Isla J, Lyon GJ, Weng C, Wang K.
Phen2Gene: rapid phenotype-driven gene prioritization for rare diseases.
NAR Genom Bioinform. 2020 Jun;2(2):lqaa032. doi: 10.1093/nargab/lqaa032. Epub 2020 May 25. PMID: 32500119; PMCID: PMC7252576.
:: DESCRIPTION
GPSy (gene prioritization system) is a high-throughput profiling experiments based on for example microarrays or proteomics yield genes potentially important for a given biological process.
::DEVELOPER
:: SCREENSHOTS
N/A
:: REQUIREMENTS
:: DOWNLOAD
NO
:: MORE INFORMATION
Citation
Nucleic Acids Res. 2012 Jul;40(Web Server issue):W458-65. doi: 10.1093/nar/gks380. Epub 2012 May 8.
GPSy: a cross-species gene prioritization system for conserved biological processes–application in male gamete development.
Britto R, Sallou O, Collin O, Michaux G, Primig M, Chalmel F.
